Coagulation tests show significant differences in patients with breast cancer

Abstract

Activated coagulation and fibrinolytic system in cancer patients is associated with tumor stroma formation and metastasis in different cancer types. The aim of this study is to explore the correlation of blood coagulation assays for various clinicopathologic factors in breast cancer patients. A total of 123 female breast cancer patients were enrolled into the study. All the patients were treatment na 50 years) was associated with higher D-dimer levels (p = 0.003). Metastatic patients exhibited significantly higher D-dimer values when compared with early breast cancer patients (p = 0.049). Advanced tumor stage (T3 and T4) was associated with higher INR (p = 0.05) and lower PTA (p = 0.025). In conclusion, coagulation tests show significant differences in patients with breast cancer.