Prognostic significance of the preoperative serum levels of soluble form of endoglin in gastric cancer patients

Abstract

Background: Gastric cancer is the second commonest cause of cancer-associated deaths in the world. Its molecular markers can be useful not only for the diagnostic pursuit but also for prognostic purposes. Endoglin was proposed as a marker of neovascularization in solid malignancies. A circulating form of endoglin is referred to as soluble endoglin (sol-end). The purpose of this study was to investigate the clinical importance of serum level of soluble form of sol-end in gastric cancer patients.