Elevated ghrelin levels in preterm born children during prepubertal ages and relationship with catch-up growth.

Abstract

Background: Ghrelin. the natural ligand of the GH secretagogue receptor. has potent orexigenic effect. Ghrelin levels are negatively associated with insulin secretion. increased in anorexia, and reduced in obesity. Increased ghrelin levels may be associated with early postnatal growth in preterm born children.