Efficacy of moxidectin against Aspiculuris tetraptera and Syphacia muris in naturally infected rats

Abstract

in this study, 56 rats (Rattus norvegicus) naturally infected with both Aspiculuris tetraptera and Syphacia muris were used. The animals were randomly divided into the treatment (37 animals) and control (19 animals) groups. Moxidectin (Cydectin enj., %1 Moxidectin) at 0.2 mg/kgbw was given subcutaneously to the treatment group. The faeces of both groups were examined on days 0, 7, 14, 21, 28. The post-mortem examination of one animal from each group was performed to confirm the EPG results on days mentioned above. The percentage efficacy was measured on the basis of the reduction of the eggs.