PYRROLIZIDINE ALKALOIDS FROM HELIOTROPIUM-BOVEI

Abstract

Heliotropium bovei was shown to contain lasiocarpine, europine, 5'-acetyllasiocarpine and a new alkaloid 7-acetyleuropine. Lasiocarpine N-oxide and 5'-acetyllasiocarpine N-oxide are also present in this plant species. These structures were established from spectral and chemical studies including 2D NMR. Europine showed both antifungal and insect antifeedant activity, while 7-acetyleuropine was inactive.