Mediastinal adipose tissue expresses a pathogenic profile of 11 beta-hydroxysteroid dehydrogenase Type 1, glucocorticoid receptor, and CD68 in patients with coronary artery disease

Date
2013
Author
Atalar, Fatmahan
Tanriverdi, Gamze
Gormez, Selcuk
Caynak, Baris
Akan, Gokce
Bilgic-Gazioglu, Sema
Gunay, Demet
Duran, Cihan
Akpinar, Belhhan
Ozbek, Ugur
Buyukdevrim, Ahmet Sevim
Yazici, Zeliha
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Abstract
Objective: Cardiac visceral fat is accepted to be a new marker for cardiometabolic risk due to its association with increased cardiovascular risk factors. This study aimed to compare the expression of 11 beta hydroxysteroid dehydrogenases (11 beta-HSD)-1, glucocorticoid receptor (GCR), and CD68 in mediastinal and subcutaneous adipose tissues (MAT, and SAT, respectively) and to assess their possible relationships with the development of coronary artery disease (CAD).
URI
http://hdl.handle.net/20.500.12627/122287
https://doi.org/10.1016/j.carpath.2012.07.006
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