EFFECTS OF TRANEXAMIC ACID ON COAGULATION AND FLAP SURVIVAL IN RATS

Abstract

Objective: Tranexamic acid (TNA) is an antifibrinolytic agent which is used to decrease blood loss during surgery. In our study, we investigated the effects of TNA on the extent of flap necrosis using random flaps in rats. Our aim was to test the safety of TNA within flap surgery.