Effects of Tarantula cubensis Extract on Electrocardiographic and Trace Element Status in Sheep

Abstract

The purpose of this research was to investigate the acute effects of Tarantula cubensis

extract (Theranekron, 1:100/D2, Richter Pharma, Austria) on some serum enzymes and

trace elements, and the cardiovascular system in sheep. Seven sheep (age 6 months, 35±10

kg) were used in this study. Theranekron was applied in 6 ml doses subcutaneously. It was

determined that in the serum Urea, Creatinin, ALT, ALP, G-GT, LDH, Ca and P levels were

increased and T. protein, Mg, Cu, Fe, Zn and Se levels were decreased. The important

results obtained after the treatment with Theranekron on cardiovascular system were

blood pressure increases and some morphological changes in ECG. We concluded the

Theranekron treatment can cause adverse effects in sheep and further investigation of the

efficacy of Theranekron treatment is warranted.