Very Important Histopathological Factors in Patients with Resected Non-Small Cell Lung Cancer: Necrosis and Perineural Invasion

Abstract

Background: The current staging system provides an anatomical classification of lung tumors; its secondary purpose is to allow the prognostic stratification of patients into homogeneous groups after surgery. In this work, intratumoral perineural invasion, lymphatic and blood vessel invasion together with the necrosis content of the tumor exclusive of the non-small cell cancer staging system were studied.