Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis

Author
Frederikson, Jette
Paul, Friedemann
Marignier, Romain
Franciotta, Diego
Ruprecht, Klemens
Kuenz, Bettina
Rommer, Paulus
Kristoferitsch, Wolfgang
Wildemann, Brigitte
Vincent, Angela
Akman-Demir, Gulsen
Jarius, Sven
Waters, Patrick
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Abstract
Background: Antibodies to aquaporin-4 (AQP4-Ab) are found in 60-80% of patients with neuromyelitis optica (NMO), a severely disabling inflammatory CNS disorder of putative autoimmune aetiology, which predominantly affects the optic nerves and spinal cord.
URI
http://hdl.handle.net/20.500.12627/120273
https://doi.org/10.1016/j.jns.2010.07.011
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