Seizure expression, behavior, and brain morphology differences in colonies of Genetic Absence Epilepsy Rats from Strasbourg

Date
2014
Author
JONES, Nigel C.
TANG, Howard
NG, Caroline
GUILLEMAIN, Isabelle
DIEUSET, Gabriel
DEZSI, Gabi
Carcak, Nihan
O'BRIEN, Terence J.
DEPAULIS, Antoine
POWELL, Kim L.
ONAT, FİLİZ
MARTIN, Benoit
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Abstract
ObjectiveOriginally derived from a Wistar rat strain, a proportion of which displayed spontaneous absence-type seizures, Genetic Absence Epilepsy Rats from Strasbourg (GAERS) represent the most widely utilized animal model of genetic generalized epilepsy. Here we compare the seizure, behavioral, and brain morphometric characteristics of four main GAERS colonies that are being actively studied internationally: two from Melbourne (MELB and STRAS-MELB), one from Grenoble (GREN), and one from Istanbul (ISTAN).
URI
http://hdl.handle.net/20.500.12627/117964
https://doi.org/10.1111/epi.12840
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