Synthesis and antiviral activity evaluation of some cyclohexylidenehydrazide derivatives of 1,3-thiazole core

Abstract

Some novel cyclohexylidenehydrazide derivatives carrying five membered heterocyclic ring, 1,3-thiazole were synthesized to investigate their antiviral (including anti-HIV) activity against diverse DNA and RNA viruses in CRFK, HeLa, HEL, MDCK, Vero and MT4 cell cultures. None of the compounds was active against any of the DNA or RNA viruses at 100 mu M.