Evaluation of application of multiple needle pricks on the pathergy reaction

Abstract

Background The pathergy reaction (PR) to a needle prick is a well-known feature of Behcet's disease (BD). Although PR is accepted as a major criterion in this disease, there is a lack of a standardized method to measure PR. The aim of this study was to evaluate the effect on the positive rate of PR of the application of numerous (one to six) needle pricks.