Correlation between H-1 MRS and memory before and after surgery in mesial temporal lobe epilepsy with hippocampal sclerosis

Abstract

Purpose: Proton magnetic resonance spectroscopy (H-1 MRS). which can demonstrate neuronal loss and gliosis, may be used as a sensitive tool for lateralization of temporal lobe epilepsy (TLE). Although the correlation between the memory functions and H-1 MRS has been investigated, its predictive value after surgery has not been studied previously. This Study evaluated memory and H-1 MRS values of medically intractable patients with mesial TLE and hippocampal sclerosis (MTLE-HS) before and after selective amygdalohippocampectomy (SAH).