SET oncogene is upregulated in pediatric acute lymphoblastic leukemia.
Date
2012Author
Agaoglu, Leyla
Ekmekci, Cumhur G.
Kandilci, Ayten
Grosveld, Gerard
Ustek, Duran
Akbiyik, Meral
Emrence, Zeliha
Gulec, Çağrı
Ozbek, Ugur
Devecioglu, Omer
Anak, Sema
Karakas, Zeynep
Unuvar, Aysegul
Abaci, Neslihan
Ekmekci, Sema Sirma
Metadata
Show full item recordAbstract
Aims and background. The SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It has been shown that SET is upregulated in BCR-ABL1-positive cell lines, patient-derived chronic myeloid leukemia CD34-positive cells, and some solid tumors.
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