Immunohistochemical Localization of Glutathione S-Transferase Isoenzymes (GSTA, GSTP, GSTM4, and GSTT1) and Tumour Marker p53 in Matched Tissue from Normal Larynx and Laryngeal Carcinoma: Correlations with Prognostic Factors
Date
2010Author
Nurdan, Gurbuz
Sedat, Aydin
Aylin, Gul
Serpil, Oguztuzun
Nimet, Karadayi
Sezen, Ozan
Bulent, Satar
Muzeyyen, Ozhavzali
Arif, Sanli
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Objective: The immunohistochemical staining characteristics of glutathione S-transferase (GST) alpha (GSTA), pi (GSTP), mu (GSTM4), and theta (GSTT1) and P53 were investigated in laryngeal squamous cell carcinoma (LSCC) cases and normal laryngeal tissue from 46 patients. The relationships between expression of the GST isoenzymes and some clinicopathologic features were also examined.
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