Clinical Impact of High-dose Intravenous Methylprednisolone for Ten Days in Relapses of Multiple Sclerosis "Treatment of Relapses in Multiple Sclerosis"
Date
2009Author
Emre, Ufuk
Kirbas, Dursun
Kuscu, Demet Y.
Yazar, Tamer
Ankarali, Handan
Unal, Aysun
Sutlas, P. Nevin
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Background: Glucocorticoid treatment is recommended as the first-line treatment of MS relapses, however there is still no clear evidence supporting an optimum therapeutic regime. The high dose (HD) consisted of at least 500 mg/day, but the total dose of intravenous MP administered and the regimen varied among studies. The aim of this study was to assess the improvement following a standard regime of IVMP (1 g/day MP given for 10 days, without tapering) for MS relapses. A second objective was to search baseline predictors of outcome.
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