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Surgical treatment of hypopharyngeal cancer

Date
2018
Author
Başaran, Bora
Kıyak, Ökkeş Erkan
Aslan, İsmet
Güneş, Selçuk
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Abstract
Objectives: This study aims to evaluate our department’s approach to the treatment of hypopharyngeal tumors, the features of the tumors, the survival analyses and to present our results in the light of the literature. Patients and Methods: Eighty-one hypopharyngeal tumor patients and four patients with undefined primary origin, those patients with undefined origin have tumors that infiltrate both hypopharynx and cervical esophagus, totally 85 patients (56 males, 29 females; mean age 54.6±13.4 years; range, 23 to 81 years) who underwent surgical treatment, were included in this study. Demographic data, tumor characteristics, and treatment protocols were recorded retrospectively. Results: Patients were classified on the primary subsite of the hypopharynx: 51% originated from the sinus piriformis, 29% from the postcricoid area, 15% from the posterior wall of the pharynx and only 5% from the cervical esophagus. The relationship between sex and hypopharyngeal subsite was statistically significant (p<0.001); postcricoid tumors were more prominent in female patients. Also, patients with a history of tobacco use had a tendency for tumors originating from the piriform sinus (p<0.001). Additionally, highly significant differences were revealed between clinical and pathological T and N staging (p<0.001). Estimated 60-month survival rate was 45%. Conclusion: The majority of patients in the study group were not old-aged or alcohol consumers; particularly none of the female patients had any bad habit as a predisposing factor suggested in the etiology. The relationships between tumor site and smoking show that if the campaign against smoking is successful, the rate of sinus piriformis cancer will decrease. For a significant number of patients, primary surgical reconstruction was possible, which shortens postoperative recovery time and accelerates postoperative adjuvant therapy. Therefore, survival rates were found to be high.
URI
http://hdl.handle.net/20.500.12627/104922
http://dx.doi.org/10.5606/Tr-ENT.2018.22931
https://doi.org/10.5606/tr-ent.2018.22931
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İstanbul Üniversitesi Akademik Arşiv Sistemi (ilgili içerikte aksi belirtilmediği sürece) Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

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Creative Commons Lisansı

İstanbul Üniversitesi Akademik Arşiv Sistemi (ilgili içerikte aksi belirtilmediği sürece) Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV