Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis
Date
2005Author
Koyuturk, M
Fraser, SP
Diss, JKJ
Chioni, AM
Mycielska, ME
Pan, HY
Yamaci, RF
Djamgoz, MBA
Pani, F
Siwy, Z
Krasowska, M
Grzywna, Z
Brackenbury, WJ
Theodorou, D
Kaya, H
Battaloglu, E
De Bella, MT
Slade, MJ
Tolhurst, R
Palmieri, C
Jiang, J
Latchman, DS
Coombes, RC
Metadata
Show full item recordAbstract
Purpose: Ion channel activity is involved in several basic cellular behaviors that are integral to metastasis (e.g., proliferation, motility, secretion, and invasion), although their contribution to cancer progression has largely been ignored. The purpose of this study was to investigate voltage-gated Na(+) channel (VGSC) expression and its possible role in human breast cancer.
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