Beat-to-beat monitoring of the sympatho-vagal balance during ischemic episodes

Abstract

In two groups of patients with Chronic Stable. Angina (CSA, 4 patients.) and Vasospastic Angina (VA, 6 patients.) we studied the role of autonomic control ibv frequency analysis of the heart variability (IIRV) signal via autoregressive (AR) models. The spectral parameters, that quantify the sympatho-vagal balance were evaluated oil 24th ECG recordings and in correspondence of ischemic events. Since the HRV signal is not stationary, the AR model was used in its time-variant form in correspondence of ischemic events. The 24th analysis in VA patients evidenced an impaired control by the autonomic nervous system. In correspondence of the ischemic events a sympathetic activation was documented. In CSA episodes the maximum of suck an activation was observed after the onset of the event, while ill VA patients the sympathetic activation reaches its maximum before the onset of the attack On the basis of these results a different autonomic involvement can he hypnotized the two different pathologies.