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Ganciclovir-resistant cytomegalovirus encephalitis in a hematopoietic stem cell transplant recipient

dc.contributor.authorTabak, Fehmi
dc.contributor.authorOzaras, Resat
dc.contributor.authorFerhanoglu, Burhan
dc.contributor.authorOzturk, Recep
dc.contributor.authorMidilli, Kenan
dc.contributor.authorArslan, Ferhat
dc.contributor.authorAvsar, Emin
dc.contributor.authorMert, Ali
dc.contributor.authorSoysal, Teoman
dc.date.accessioned2021-03-04T18:16:47Z
dc.date.available2021-03-04T18:16:47Z
dc.date.issued2010
dc.identifier.citationArslan F., Tabak F., Avsar E., Midilli K., Mert A., Ozaras R., Soysal T., Ozturk R., Ferhanoglu B., "Ganciclovir-resistant cytomegalovirus encephalitis in a hematopoietic stem cell transplant recipient", JOURNAL OF NEUROVIROLOGY, cilt.16, ss.174-178, 2010
dc.identifier.issn1355-0284
dc.identifier.othervv_1032021
dc.identifier.otherav_89d4e8de-adb9-46a0-ae61-a0603fabdf91
dc.identifier.urihttp://hdl.handle.net/20.500.12627/93467
dc.identifier.urihttps://doi.org/10.3109/13550281003682539
dc.description.abstractWe describe a 41-year-old patient, who upon receiving a bone marrow transplant in order to treat chronic myeloid leukemia, developed cytomegalovirus (CNV) retinitis and encephalitis under the ganciclovir maintenance treatment. Analysis of sequential viral isolates recovered from the patient's cerebrospinal fluid and blood showed CMV DNA with a UL97 mutation (M460V) known to confer ganciclovir resistance. Foscarnet resistance mutations were not found. Although therapy was switched to foscarnet when ganciclovir resistance was suspected, the patient was lost on posttransplant day 200.
dc.language.isoeng
dc.subjectMikrobiyoloji ve Klinik Mikrobiyoloji
dc.subjectViroloji
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectİmmünoloji
dc.subjectVİROLOJİ
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSinirbilim ve Davranış
dc.subjectNEUROSCIENCES
dc.titleGanciclovir-resistant cytomegalovirus encephalitis in a hematopoietic stem cell transplant recipient
dc.typeMakale
dc.relation.journalJOURNAL OF NEUROVIROLOGY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume16
dc.identifier.issue2
dc.identifier.startpage174
dc.identifier.endpage178
dc.contributor.firstauthorID40970


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