Results of resection of pulmonary metastasis and prognostic factors

Abstract

Background: In this study, we investigated the survival outcomes of metastasectomy and prognostic factors affecting survival.

Methods: Between January 2004 and March 2012, a total of 85 patients (44 males, 41 females; mean age 51 years; range 15 to 85 years) who were operated for metastatic lung disease in our clinic were retrospectively analyzed. Possible effects of clinical and radiological findings on postoperative outcomes were assessed.

Results: A total of 118 surgical procedures were performed in 85 patients. Thoracotomy was the most common intervention performed in 104 patients (88%). The second most frequent intervention was video-assisted thoracoscopic surgery in 12 patients (10%). Three-year survival rate was 85%, while five-year survival rate was 62.5% in patients undergoing lung metastasectomy. Three-year survival was found to be 76% in patients with primary carcinoma and 37% in non-carcinoma patients. Lymph node involvement was not found to be a prognostic factor in patients with colorectal carcinoma (p>0.05). The mean survival was 35 +/- 2.1 months and two-year survival was 50% in patients who were operated for metastatic lung disease of breast carcinoma.

Conclusion: Good survival rates can be achieved in patients undergoing lung metastasectomy. We believe that histopathology of the primary tumor is the main prognostic factor for survival.