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High rate of aneuploidy in luteinized granulosa cells obtained from follicular fluid in women who underwent controlled ovarian hyperstimulation

dc.contributor.authorTopcuoglu, A
dc.contributor.authorIrez, T
dc.contributor.authorKaleli, Semih
dc.contributor.authorYanikkaya-Demirel, G
dc.contributor.authorErel, CT
dc.contributor.authorSenturk, LM
dc.date.accessioned2021-03-04T17:35:38Z
dc.date.available2021-03-04T17:35:38Z
dc.date.issued2005
dc.identifier.citationKaleli S., Yanikkaya-Demirel G., Erel C., Senturk L., Topcuoglu A., Irez T., "High rate of aneuploidy in luteinized granulosa cells obtained from follicular fluid in women who underwent controlled ovarian hyperstimulation", FERTILITY AND STERILITY, cilt.84, sa.3, ss.802-804, 2005
dc.identifier.issn0015-0282
dc.identifier.othervv_1032021
dc.identifier.otherav_865f8f93-b97b-4718-b0a5-d28f1c2cbdd7
dc.identifier.urihttp://hdl.handle.net/20.500.12627/91310
dc.identifier.urihttps://doi.org/10.1016/j.fertnstert.2005.02.040
dc.description.abstractWe performed a prospective study to detect the cell cycle changes in luteinized granulosa cells in patients undergoing controlled ovarian stimulation with GnRH analog and gonadotropin therapy. Aneuploid DNA content was observed in 37 of 70 women (52.9%), and multiple logistic regression analysis revealed that only the dose of gonadotropins used significantly predicted the ploidy status of granulosa cells, which indicates that ovarian hyperstimulation in IVF treatment might be detrimental for the DNA content of granulosa cells.
dc.language.isoeng
dc.subjectYaşam Bilimleri
dc.subjectBiochemistry (medical)
dc.subjectHealth Sciences
dc.subjectKADIN HASTALIKLARI & DOĞUM
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectÜREME BİYOLOJİSİ
dc.subjectBiyoloji ve Biyokimya
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectBiyokimya
dc.subjectCerrahi Tıp Bilimleri
dc.subjectKadın Hastalıkları ve Doğum
dc.subjectTemel Bilimler
dc.subjectObstetrics and Gynecology
dc.titleHigh rate of aneuploidy in luteinized granulosa cells obtained from follicular fluid in women who underwent controlled ovarian hyperstimulation
dc.typeMakale
dc.relation.journalFERTILITY AND STERILITY
dc.contributor.department, ,
dc.identifier.volume84
dc.identifier.issue3
dc.identifier.startpage802
dc.identifier.endpage804
dc.contributor.firstauthorID176169


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