dc.contributor.author | Baki, Ali | |
dc.contributor.author | KÜTÜKÇÜLER, NECİL | |
dc.contributor.author | Yilmaz, Mustafa | |
dc.contributor.author | Ikinciogullari, Aydan | |
dc.contributor.author | Yegin, Olcay | |
dc.contributor.author | YUEKSEK, Mutlu | |
dc.contributor.author | GENEL, Ferah | |
dc.contributor.author | Kucukosmanoglu, Ercan | |
dc.contributor.author | Bahceciler, Nerin N. | |
dc.contributor.author | RAMBHATLA, Anupama | |
dc.contributor.author | NICKERSON, Derek W. | |
dc.contributor.author | MCGHEE, Sean | |
dc.contributor.author | Barlan, Isil B. | |
dc.contributor.author | CHATILA, Talal | |
dc.contributor.author | AL KHATIB, Shadi | |
dc.contributor.author | Keles, Sevgi | |
dc.contributor.author | GARCIA-LIORET, Maria | |
dc.contributor.author | Koc-Aydiner, Elif Kara | |
dc.contributor.author | Reisli, Ismail | |
dc.contributor.author | Artac, Hasibe | |
dc.contributor.author | Camcioglu, Yildiz | |
dc.contributor.author | Cokugras, Haluk | |
dc.contributor.author | Somer, Ayper | |
dc.date.accessioned | 2021-03-04T14:37:55Z | |
dc.date.available | 2021-03-04T14:37:55Z | |
dc.date.issued | 2009 | |
dc.identifier.citation | AL KHATIB S., Keles S., GARCIA-LIORET M., Koc-Aydiner E. K. , Reisli I., Artac H., Camcioglu Y., Cokugras H., Somer A., KÜTÜKÇÜLER N., et al., "Defects along the T(H)17 differentiation pathway underlie genetically distinct forms of the hyper IgE syndrome", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, cilt.124, sa.2, ss.342-348, 2009 | |
dc.identifier.issn | 0091-6749 | |
dc.identifier.other | av_8290f08d-c160-4ea5-8118-ceb9ee300b53 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/88924 | |
dc.identifier.uri | https://doi.org/10.1016/j.jaci.2009.05.004 | |
dc.description.abstract | Background: The hyper IgE syndrome (HIES) is characterized by abscesses, eczema, recurrent infections, skeletal and connective tissue abnormalities, elevated serum IgE, and diminished inflammatory responses. It exists as autosomal-dominant and autosomal-recessive forms that manifest common and distinguishing clinical features. A majority of those with autosomal-dominant HIES have heterozygous mutations in signal transducer and activator of transcription (STAT)-3 and impaired T(H)17 differentiation. | |
dc.language.iso | eng | |
dc.subject | Sağlık Bilimleri | |
dc.subject | ALERJİ | |
dc.subject | Klinik Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | İmmünoloji | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Tıp | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.title | Defects along the T(H)17 differentiation pathway underlie genetically distinct forms of the hyper IgE syndrome | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | |
dc.contributor.department | Ege Üniversitesi , Tıp Fakültesi , Dahili Tıp Bilimleri Bölümü | |
dc.identifier.volume | 124 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 342 | |
dc.identifier.endpage | 348 | |
dc.contributor.firstauthorID | 38651 | |