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Characterization of cancer stem-like cells in chordoma Laboratory investigation

dc.contributor.authorYalvac, Mehmet Emir
dc.contributor.authorOzen, Mustafa
dc.contributor.authorSevli, Serhat
dc.contributor.authorDogruluk, Turgut
dc.contributor.authorTure, Ugur
dc.contributor.authorDalan, Altay Burak
dc.contributor.authorAydemir, Esra
dc.contributor.authorBayrak, Omer Faruk
dc.contributor.authorSahin, Fikrettin
dc.contributor.authorAtalay, Basar
dc.contributor.authorKose, Gamze Torun
dc.date.accessioned2021-03-04T14:33:07Z
dc.date.available2021-03-04T14:33:07Z
dc.date.issued2012
dc.identifier.citationAydemir E., Bayrak O. F. , Sahin F., Atalay B., Kose G. T. , Ozen M., Sevli S., Dalan A. B. , Yalvac M. E. , Dogruluk T., et al., "Characterization of cancer stem-like cells in chordoma Laboratory investigation", JOURNAL OF NEUROSURGERY, cilt.116, sa.4, ss.810-820, 2012
dc.identifier.issn0022-3085
dc.identifier.othervv_1032021
dc.identifier.otherav_822b34f2-adf4-45e2-8d4b-3e73c4040ede
dc.identifier.urihttp://hdl.handle.net/20.500.12627/88654
dc.identifier.urihttps://doi.org/10.3171/2011.12.jns11430
dc.description.abstractObject. Chordomas are locally aggressive bone tumors known to arise from the remnants of the notochord. Because chordomas are rare, molecular studies aimed at developing new therapies are scarce and new approaches are needed. Chordoma cells and cancer stem-like cells share similar characteristics, including self-renewal, differentiation, and resistance to chemotherapy. Therefore, it seems possible that chordomas might contain a subpopulation of cancer stem-like cells. The aim of this study is to determine whether cancer stem-like cells might be present in chordomas.
dc.language.isoeng
dc.subjectCerrahi Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectTıp
dc.subjectCERRAHİ
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKLİNİK NEUROLOJİ
dc.subjectNöroloji
dc.titleCharacterization of cancer stem-like cells in chordoma Laboratory investigation
dc.typeMakale
dc.relation.journalJOURNAL OF NEUROSURGERY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume116
dc.identifier.issue4
dc.identifier.startpage810
dc.identifier.endpage820
dc.contributor.firstauthorID58586


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