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Perampanel in Parkinson Disease Fluctuations: A Double-Blind Randomized Trial With Placebo and Entacapone

dc.contributor.authorSquillacote, David
dc.contributor.authorTolosa, Eduardo
dc.contributor.authorPatten, Anna
dc.contributor.authorBibbiani, Francesco
dc.contributor.authorEmre, Murat
dc.contributor.authorRascol, Olivier
dc.contributor.authorBarone, Paolo
dc.contributor.authorBehari, Madhuri
dc.contributor.authorGiladi, Nir
dc.contributor.authorOlanow, C. Warren
dc.contributor.authorRuzicka, Evzen
dc.date.accessioned2021-03-04T14:05:58Z
dc.date.available2021-03-04T14:05:58Z
dc.date.issued2012
dc.identifier.citationRascol O., Barone P., Behari M., Emre M., Giladi N., Olanow C. W. , Ruzicka E., Bibbiani F., Squillacote D., Patten A., et al., "Perampanel in Parkinson Disease Fluctuations: A Double-Blind Randomized Trial With Placebo and Entacapone", CLINICAL NEUROPHARMACOLOGY, cilt.35, sa.1, ss.15-20, 2012
dc.identifier.issn0362-5664
dc.identifier.othervv_1032021
dc.identifier.otherav_7fc250be-f7a6-4817-b940-d1cdfac8fe6a
dc.identifier.urihttp://hdl.handle.net/20.500.12627/87176
dc.identifier.urihttps://doi.org/10.1097/wnf.0b013e318241520b
dc.description.abstractObjectives: Perampanel is a selective and noncompetitive alpha-amino-3-hydroxy-5-methylisoxazole propionic acid-type glutamate receptor antagonist that improves motor symptoms in animal models of Parkinson disease (PD). The aim of this study was to assess the efficacy and tolerability of perampanel in L-dopa-treated patients with moderately severe PD and motor fluctuations using an active comparator study design.
dc.language.isoeng
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectNöroloji
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKLİNİK NEUROLOJİ
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.titlePerampanel in Parkinson Disease Fluctuations: A Double-Blind Randomized Trial With Placebo and Entacapone
dc.typeMakale
dc.relation.journalCLINICAL NEUROPHARMACOLOGY
dc.contributor.departmentUniversité De Toulouse-Le Mirail: Toulouse Iı , ,
dc.identifier.volume35
dc.identifier.issue1
dc.identifier.startpage15
dc.identifier.endpage20
dc.contributor.firstauthorID203280


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