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Cox-2 gene variants in migraine

dc.contributor.authorCakmakoglu, Bedia
dc.contributor.authorOzkok, Elif
dc.contributor.authorÇetinkaya, Yilmaz
dc.contributor.authorAydin, Makbule
dc.contributor.authorGencer, Mehmet
dc.contributor.authorDasdemir, Selcuk
dc.date.accessioned2021-03-04T13:42:45Z
dc.date.available2021-03-04T13:42:45Z
dc.date.issued2013
dc.identifier.citationDasdemir S., Çetinkaya Y., Gencer M., Ozkok E., Aydin M., Cakmakoglu B., "Cox-2 gene variants in migraine", Gene, cilt.518, sa.2, ss.292-295, 2013
dc.identifier.issn0378-1119
dc.identifier.othervv_1032021
dc.identifier.otherav_7dd3b17b-edde-4053-b3ea-43a905d9febb
dc.identifier.urihttp://hdl.handle.net/20.500.12627/85951
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875378775&origin=inward
dc.identifier.urihttps://doi.org/10.1016/j.gene.2012.12.110
dc.description.abstractPurpose: Migraine is a multifactorial and complex disorder, and any clear diagnostic marker to assess the status of the migraineurs has not been established, yet. Nonsteroidal anti-inflammatory drugs reduce production of prostanoids including PGE2 by inhibiting COX-1 and/or COX-2, and thereby suppress inflammatory pain in patients suffering from rheumatoid arthritis, osteoarthritis, and migraine. Thus, COX-2 regulation is important in the pathogenesis and treatment of migraine. We prospectively investigated COX-2-765G -> C and COX-2-1195A -> G gene polymorphisms which may account for an increased risk of migraine.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectDahili Tıp Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTıbbi Genetik
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectGENETİK VE HAYAT
dc.titleCox-2 gene variants in migraine
dc.typeMakale
dc.relation.journalGene
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume518
dc.identifier.issue2
dc.identifier.startpage292
dc.identifier.endpage295
dc.contributor.firstauthorID69051


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