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dc.contributor.authorOZBEK, Z.
dc.contributor.authorAydın, Muhammet
dc.contributor.authorKara, I.
dc.contributor.authorOzkok, Elif
dc.contributor.authorKucukali, I. Cem
dc.date.accessioned2021-03-04T13:21:38Z
dc.date.available2021-03-04T13:21:38Z
dc.identifier.citationOzkok E., Aydın M., OZBEK Z., Kucukali I. C. , Kara I., "Is elevated homocysteine level a risk factor for bipolar disorder?", 13th Biennial Meeting of the Society-for-Free-Radical-Research-International, Davos, İsviçre, 15 - 19 Ağustos 2006, ss.279-282
dc.identifier.othervv_1032021
dc.identifier.otherav_7c0a9724-7e3b-4fa6-953a-c3a7b1520bea
dc.identifier.urihttp://hdl.handle.net/20.500.12627/84840
dc.description.abstractHomocysteine levels have been reported to be elevated in psychiatric patients. We investigated the homocysteine levels in bipolar patients, their first-degree relatives and normal healthy controls. The study comprised of two hundred seven patients with bipolar affective disorder, two hundred ninety-eight relatives of patients and three hundred forty normal subjects. Homocysteine level was found significantly higher in patients and their relatives compared to controls. We also found significant negative correlation between homocysteine and HDL-cholesterol in patients with bipolar affective disorder. In conclusion, increased homocysteine levels might result from low HDL-cholesterol and high triglyceride and cholesterol that cause oxidative stress that is more pronounced in psychiatric disorders. Subjects who have elevated homocysteine might be sensitive to develope bipolar disorders compared to healthy subjects.
dc.language.isoeng
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.titleIs elevated homocysteine level a risk factor for bipolar disorder?
dc.typeBildiri
dc.contributor.departmentEyup State Hospital , ,
dc.contributor.firstauthorID38567


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