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dc.contributor.authorÖZKAYA, EMİN
dc.contributor.authorKesgin, Siddika
dc.contributor.authorYAZICI, MEBRURE
dc.contributor.authorKOÇYİĞİT, ABDÜRRAHİM
dc.contributor.authorOzceker, Deniz
dc.contributor.authorGuler, Nermin
dc.contributor.authorTamay, Zeynep Ülker
dc.contributor.authorDilek, Fatih
dc.date.accessioned2021-03-04T11:27:26Z
dc.date.available2021-03-04T11:27:26Z
dc.identifier.citationDilek F., Ozceker D., ÖZKAYA E., Guler N., Tamay Z. Ü. , Kesgin S., YAZICI M., KOÇYİĞİT A., "Oxidative Stress in Children with Chronic Spontaneous Urticaria.", Oxidative medicine and cellular longevity, cilt.2016, ss.3831071, 2016
dc.identifier.issn1942-0900
dc.identifier.othervv_1032021
dc.identifier.otherav_726e644a-e1a9-446f-a7fd-4ecfa7d5a40e
dc.identifier.urihttp://hdl.handle.net/20.500.12627/78761
dc.identifier.urihttps://doi.org/10.1155/2016/3831071
dc.description.abstractThe pathogenesis of chronic spontaneous urticaria (CSU) has not been fully understood; nevertheless, significant progress has been achieved in recent years. The aim of this study was to investigate the possible role of reactive oxygen species (ROS) in the pathogenesis of CSU. Sixty-two children with CSU and 41 healthy control subjects were enrolled in the study. An extensive evaluation of demographic and clinical features was done, and serum oxidative stress was evaluated by plasma total oxidant status (TOS) and total antioxidant status (TAS) measurements. The median value of plasma TOS was found to be 10.49 mu mol H2O2 equiv./L (interquartile range, 7.29-17.65) in CSU patients and 7.68 mu mol H2O2 equiv./L (5.95-10.39) in the control group. The difference between the groups was statistically significant (p = 0.003). Likewise, the median plasma TAS level in the CSU group was decreased significantly compared to that of the control group (2.64 [2.30-2.74] versus 2.76 [2.65-2.86] mmol Trolox equiv./L, resp., p = 0,001). Our results indicated that plasma oxidative stress is increased in children with CSU when compared to healthy subjects, and plasma oxidative stress markers are positively correlated with disease activity.
dc.language.isoeng
dc.subjectHistoloji-Embriyoloji
dc.subjectHÜCRE BİYOLOJİSİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTemel Bilimler
dc.titleOxidative Stress in Children with Chronic Spontaneous Urticaria.
dc.typeMakale
dc.relation.journalOxidative medicine and cellular longevity
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume2016
dc.identifier.startpage3831071
dc.identifier.endpage3831071
dc.contributor.firstauthorID228706


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