dc.contributor.author | Madazli, Riza | |
dc.contributor.author | Bulut, Berk | |
dc.contributor.author | Gezer, Altay | |
dc.contributor.author | Kucur, Mine | |
dc.contributor.author | Isman, Ferruh | |
dc.date.accessioned | 2021-03-04T11:14:54Z | |
dc.date.available | 2021-03-04T11:14:54Z | |
dc.date.issued | 2008 | |
dc.identifier.citation | Madazli R., Kucur M., Gezer A., Isman F., Bulut B., "Chitotriosidase and YKL-40 in normal and pre-eclamptic pregnancies", INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, cilt.100, sa.3, ss.239-243, 2008 | |
dc.identifier.issn | 0020-7292 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_715a8a85-057b-4ca9-aee4-a5a79d15872d | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/78095 | |
dc.identifier.uri | https://doi.org/10.1016/j.ijgo.2007.09.033 | |
dc.description.abstract | Objective: To compare macrophage activation in normal and pre-eclamptic pregnancies by determining YKL-40 concentration and chitotriosidase activity in maternal and cord serum. Methods: In this prospective case-control study samples of maternal peripheral blood and umbilical venous blood were collected from 28 pre-eclamptic and 24 normotensive pregnant women and their newborns. YKL-40 concentration and chitotriosidase activity were determined by enzyme-linked immunoassay and fluorometry, respectively. Results: Chitotriosidase activity in maternal and cord serum and YKL-40 concentration in cord serum were significantly higher in pre-eclamptic pregnancies (P 0.001), but there was no significant difference in maternal serum levels of YKL-40 between the case and control groups (P>0.05). There was a significant positive correlation between diastolic blood pressure and (1) chitotriosidase activity in both maternal and cord serum and (2) cord serum concentration of YKL-40 (r=0.61, r=0.84, and r=0.58, respectively). Conclusion: This study may be the first to demonstrate maternal and fetal macrophage activation in pre-eclampsia. (c) 2007 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. | |
dc.language.iso | eng | |
dc.subject | Kadın Hastalıkları ve Doğum | |
dc.subject | Cerrahi Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | KADIN HASTALIKLARI & DOĞUM | |
dc.title | Chitotriosidase and YKL-40 in normal and pre-eclamptic pregnancies | |
dc.type | Makale | |
dc.relation.journal | INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | |
dc.contributor.department | Istanbul Gaziosmanpasa Taksim Training & Research Hospital , , | |
dc.identifier.volume | 100 | |
dc.identifier.issue | 3 | |
dc.identifier.startpage | 239 | |
dc.identifier.endpage | 243 | |
dc.contributor.firstauthorID | 186892 | |