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dc.contributor.authorKABASAKAL, LEVENT
dc.contributor.authorKaya, Mehmet
dc.contributor.authorUysal, Meral Keyer
dc.contributor.authorŞİRVANCI, SERAP
dc.contributor.authorERCAN, FERİHA
dc.contributor.authorToklu, Hale Z.
dc.date.accessioned2021-03-04T11:07:34Z
dc.date.available2021-03-04T11:07:34Z
dc.date.issued2009
dc.identifier.citationToklu H. Z. , Uysal M. K. , KABASAKAL L., ŞİRVANCI S., ERCAN F., Kaya M., "The Effects of Riluzole on Neurological, Brain Biochemical, and Histological Changes in Early and Late Term of Sepsis in Rats", JOURNAL OF SURGICAL RESEARCH, cilt.152, sa.2, ss.238-248, 2009
dc.identifier.issn0022-4804
dc.identifier.othervv_1032021
dc.identifier.otherav_70b30ac2-ca69-4265-9b19-c8ec3a3480cd
dc.identifier.urihttp://hdl.handle.net/20.500.12627/77670
dc.identifier.urihttps://doi.org/10.1016/j.jss.2008.03.013
dc.description.abstractObjective. One of the underlying mechanisms of sepsis is thought to be the oxidative damage due to the generation of free radicals. Glutamate, the major excitatory amino acid in the brain, is known to play an important role in blood brain barrier (BBB) permeability, brain edema, and oxidative damage in pathological conditions. Riluzole, a glutamate release inhibitor, has been shown to have neuroprotective effects in several animal models. The aim of our study was to investigate the putative protective effect of riluzole against sepsis-induced brain injury.
dc.language.isoeng
dc.subjectKlinik Tıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectCERRAHİ
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.titleThe Effects of Riluzole on Neurological, Brain Biochemical, and Histological Changes in Early and Late Term of Sepsis in Rats
dc.typeMakale
dc.relation.journalJOURNAL OF SURGICAL RESEARCH
dc.contributor.departmentMarmara Üniversitesi , ,
dc.identifier.volume152
dc.identifier.issue2
dc.identifier.startpage238
dc.identifier.endpage248
dc.contributor.firstauthorID192042


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