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dc.contributor.authorYosunkaya-Fenerci, E
dc.contributor.authorBuyru, N
dc.contributor.authorDalay, N
dc.contributor.authorTezol, A
dc.date.accessioned2021-03-04T11:06:10Z
dc.date.available2021-03-04T11:06:10Z
dc.date.issued2003
dc.identifier.citationBuyru N., Tezol A., Yosunkaya-Fenerci E., Dalay N., "Vitamin D receptor gene polymorphisms in breast cancer", EXPERIMENTAL AND MOLECULAR MEDICINE, cilt.35, sa.6, ss.550-555, 2003
dc.identifier.issn1226-3613
dc.identifier.othervv_1032021
dc.identifier.otherav_70a08e04-011b-460a-b5b5-a3e1edaebadf
dc.identifier.urihttp://hdl.handle.net/20.500.12627/77622
dc.identifier.urihttps://doi.org/10.1038/emm.2003.72
dc.description.abstractBreast cancer is the leading cause of cancer death among women around the world and its incidence is annually increasing. The vitamin D receptor (VDR) gene is a member of the nuclear receptor superfamily, which is expressed in breast tissue and known to modulate the rate of cell proliferation. Association between the VDR gene polymorphisms and cancer development has been suggested by several studies. However, the relationship between VDR polymorphisms and breast cancer is controversial and has not been confirmed by all studies. The purpose of this study was to investigate the genotype frequencies and association of the VDR Bsm I and Taq I polymorphisms with breast cancer in Turkish patients. In this study, 78 patients with breast cancer and 27 healthy individuals were. enrolled. The prevalence of the VDR Taq I and Bsm I alleles and the genotype frequencies in patients with breast cancer was similar to that in the normal population. Our data indicate that no significant differences exist between the patients and control subjects.
dc.language.isoeng
dc.subjectDahili Tıp Bilimleri
dc.subjectTıbbi Ekoloji ve Hidroklimatoloji
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIP, ARAŞTIRMA VE DENEYSEL
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.titleVitamin D receptor gene polymorphisms in breast cancer
dc.typeMakale
dc.relation.journalEXPERIMENTAL AND MOLECULAR MEDICINE
dc.contributor.department, ,
dc.identifier.volume35
dc.identifier.issue6
dc.identifier.startpage550
dc.identifier.endpage555
dc.contributor.firstauthorID169996


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