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Ketamine and its combinations with valproate and carbamazepine are ineffective against convulsions induced by atropine treatment and food intake in fasted mice

dc.contributor.authorTurkmen, Asli Zengin
dc.contributor.authorEnginar, Nurhan
dc.contributor.authorNURTEN, ASİYE
dc.contributor.authorGozuacik, Neriman
dc.date.accessioned2021-03-04T10:03:49Z
dc.date.available2021-03-04T10:03:49Z
dc.date.issued2019
dc.identifier.citationGozuacik N., Turkmen A. Z. , NURTEN A., Enginar N., "Ketamine and its combinations with valproate and carbamazepine are ineffective against convulsions induced by atropine treatment and food intake in fasted mice", IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, cilt.22, sa.3, ss.310-314, 2019
dc.identifier.issn2008-3866
dc.identifier.otherav_6b57bddc-a731-4843-8eda-fbd120c93734
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/74233
dc.identifier.urihttps://doi.org/10.22038/ijbms.2019.33890.8062
dc.description.abstractObjective(s): Fasted rodents treated with antimuscarinics develop convulsions after refeeding. Food deprivation for 48 hr produces changes in [3H]glutamate binding suggesting glutamatergic contribution to the underlying mechanism of the seizures that are somewhat unresponsive to antiepileptics. Studies in animals and epileptic patients yielded considerable information regarding the anticonvulsant effect of the noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine. Thus, this study evaluated the efficacy of ketamine and its combinations with valproate and carbamazepine on convulsions in fasted animals.
dc.language.isoeng
dc.subjectDahili Tıp Bilimleri
dc.subjectTıbbi Ekoloji ve Hidroklimatoloji
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectTIP, ARAŞTIRMA VE DENEYSEL
dc.titleKetamine and its combinations with valproate and carbamazepine are ineffective against convulsions induced by atropine treatment and food intake in fasted mice
dc.typeMakale
dc.relation.journalIRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume22
dc.identifier.issue3
dc.identifier.startpage310
dc.identifier.endpage314
dc.contributor.firstauthorID262886


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