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The evaluation of endothelin 1 (EDN1) and endothelin receptor type A (EDNRA) gene polymorphisms in Hashimoto's thyroiditis

dc.contributor.authorUysal, Mujdat
dc.contributor.authorAydın, Ali Fuat
dc.contributor.authorVural, Pervin
dc.contributor.authorDogru-Abbasoglu, Semra
dc.contributor.authorOruc, Coskun Umut
dc.contributor.authorOZDERYA, Aysenur
dc.contributor.authorKARADAG, Berlin
dc.date.accessioned2021-03-04T08:06:23Z
dc.date.available2021-03-04T08:06:23Z
dc.date.issued2014
dc.identifier.citationAydın A. F. , Vural P., Oruc C. U. , Dogru-Abbasoglu S., OZDERYA A., KARADAG B., Uysal M., "The evaluation of endothelin 1 (EDN1) and endothelin receptor type A (EDNRA) gene polymorphisms in Hashimoto's thyroiditis", INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.21, sa.1, ss.181-185, 2014
dc.identifier.issn1567-5769
dc.identifier.otherav_619690ca-5a96-48bb-aee2-1ba5ff7bc22c
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/68013
dc.identifier.urihttps://doi.org/10.1016/j.intimp.2014.04.023
dc.description.abstractPurpose: Endothelin1 (EDN1) is well established marker of inflammation. The functions of EDN1 are mediated mainly by endothelin receptors type A (EDNRA). The etiopathogenesis of Hashimoto's thyroiditis (HT) remains still elusive although the role of chronic inflammation and subsequent endothelial dysfunction has been established. This study examined firstly the possible association of EDN1 (G5665T and T-1370G) and EDNRA (C+70G and G-231A) single nucleotide polymorphisms (SNPs) with the occurrence of HT, and evaluates the relationship between genotypes and clinical/laboratory manifestation of HT.
dc.language.isoeng
dc.subjectEczacılık
dc.subjectTemel Bilimler
dc.subjectYaşam Bilimleri
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectSağlık Bilimleri
dc.subjectTemel Eczacılık Bilimleri
dc.subjectİmmünoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.titleThe evaluation of endothelin 1 (EDN1) and endothelin receptor type A (EDNRA) gene polymorphisms in Hashimoto's thyroiditis
dc.typeMakale
dc.relation.journalINTERNATIONAL IMMUNOPHARMACOLOGY
dc.contributor.departmentIstanbul Sisli Hamidiye Etfal Training & Research Hospital , ,
dc.identifier.volume21
dc.identifier.issue1
dc.identifier.startpage181
dc.identifier.endpage185
dc.contributor.firstauthorID44518


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