dc.contributor.author | Kucukyurt, Selin | |
dc.contributor.author | EŞKAZAN, Ahmet Emre | |
dc.date.accessioned | 2021-03-03T21:14:56Z | |
dc.date.available | 2021-03-03T21:14:56Z | |
dc.identifier.citation | Kucukyurt S., EŞKAZAN A. E. , "Assessment and Monitoring of Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura (iTTP): Strategies to Improve Outcomes", JOURNAL OF BLOOD MEDICINE, cilt.11, ss.319-326, 2020 | |
dc.identifier.other | av_5e2ef0ac-8222-48a3-856a-8ac1b66b3c2d | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/65872 | |
dc.identifier.uri | https://doi.org/10.2147/jbm.s205630 | |
dc.description.abstract | Background: Acquired or immune-mediated TTP (iTTP) is a life-threatening thrombotic microangiopathy, characterized by the presence of microangiopathic hemolytic anemia and severe thrombocytopenia, and a variable degree of ischemic organ damage, related to a severe deficiency of ADAMTS13, which is a serine metalloprotease necessary for cleavage of large vWF multimers. There has been a dramatic decrease in mortality rates with the recognition of the pathophysiology of iTTP over the years. Although therapeutic plasma exchange (TPE) together with corticosteroids are the backbone of the upfront treatment of patients with iTTP with successful outcomes, patients may remain refractory and/or relapse following an initial response to this treatment. | |
dc.language.iso | eng | |
dc.subject | İç Hastalıkları | |
dc.subject | Hematoloji | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Klinik Tıp | |
dc.subject | HEMATOLOJİ | |
dc.title | Assessment and Monitoring of Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura (iTTP): Strategies to Improve Outcomes | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF BLOOD MEDICINE | |
dc.contributor.department | İstanbul Üniversitesi-Cerrahpaşa , , | |
dc.identifier.volume | 11 | |
dc.identifier.startpage | 319 | |
dc.identifier.endpage | 326 | |
dc.contributor.firstauthorID | 2275879 | |