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Reduction of edema and infarction by memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat

dc.contributor.authorIzgi, N
dc.contributor.authorCobanoglu, Seçkin
dc.contributor.authorUnal, Fatih Erman
dc.contributor.authorYanik, Burcu
dc.contributor.authorKucuk, Mutlu
dc.contributor.authorGorgulu, A
dc.contributor.authorKins, T
dc.date.accessioned2021-03-03T20:40:30Z
dc.date.available2021-03-03T20:40:30Z
dc.date.issued2000
dc.identifier.citationGorgulu A., Kins T., Cobanoglu S., Unal F. E. , Izgi N., Yanik B., Kucuk M., "Reduction of edema and infarction by memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat", ACTA NEUROCHIRURGICA, cilt.142, sa.11, ss.1287-1292, 2000
dc.identifier.issn0001-6268
dc.identifier.otherav_5b2b743d-8cf5-41fd-a739-e5f15bde5aeb
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/64016
dc.identifier.urihttps://doi.org/10.1007/s007010070027
dc.description.abstractN-methyl-D-aspartate (NMDA) receptor antagonists have been found to be protective after cerebral ischemia. However most of these drugs have limited value as neuroprotectives in clinical therapy because of their side effects. Memantine is a noncompetitive NMDA receptor antagonist and it has been used for the treatment of various cerebral disorders with relatively few side effects. We investigated the beneficial effects of Memantine and compared its effect with MK-801 in a temporary focal cerebral ischemia model.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectCerrahi Tıp Bilimleri
dc.subjectNöroloji
dc.subjectCERRAHİ
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectKLİNİK NEUROLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.titleReduction of edema and infarction by memantine and MK-801 after focal cerebral ischaemia and reperfusion in rat
dc.typeMakale
dc.relation.journalACTA NEUROCHIRURGICA
dc.contributor.departmentTrakya Üniversitesi , ,
dc.identifier.volume142
dc.identifier.issue11
dc.identifier.startpage1287
dc.identifier.endpage1292
dc.contributor.firstauthorID5642


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