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Transdermal Scopolamine for the Prevention of Postoperative Nausea and Vomiting: A Systematic Review and Meta-Analysis

dc.contributor.authorFERO, Katherine E.
dc.contributor.authorCakmakkaya, Ozlem S.
dc.contributor.authorHEIDRICH, Felix
dc.contributor.authorHORNUSS, Cyrill
dc.contributor.authorPergolizzi, Joseph V.
dc.contributor.authorKRANKE, Peter
dc.contributor.authorAPFEL, Christian C.
dc.contributor.authorZHANG, Kun
dc.contributor.authorGEORGE, Elizabeth
dc.contributor.authorSHI, Serena
dc.contributor.authorJALOTA, Leena
dc.date.accessioned2021-03-03T18:03:15Z
dc.date.available2021-03-03T18:03:15Z
dc.date.issued2010
dc.identifier.citationAPFEL C. C. , ZHANG K., GEORGE E., SHI S., JALOTA L., HORNUSS C., FERO K. E. , HEIDRICH F., Pergolizzi J. V. , Cakmakkaya O. S. , et al., "Transdermal Scopolamine for the Prevention of Postoperative Nausea and Vomiting: A Systematic Review and Meta-Analysis", CLINICAL THERAPEUTICS, cilt.32, sa.12, ss.1987-2002, 2010
dc.identifier.issn0149-2918
dc.identifier.otherav_4ceb8ede-a65a-4650-a81b-eed31bd4cf5a
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/55055
dc.identifier.urihttps://doi.org/10.1016/j.clinthera.2010.11.014
dc.description.abstractBackground: Transdermal scopolamine (TDS) is a potential long-acting prophylactic antiemetic initially developed to prevent motion sickness. TDS is a centrally acting anticholinergic agent that was approved in 2001 by the US Food and Drug Administration for the prevention of postoperative nausea and vomiting (PONV). Although TDS has been reported to be clinically efficacious in the prevention of PONV, several adverse events (AEs), such as sedation, dry mouth, blurred vision, central cholinergic syndrome, and confusion (particularly in elderly patients with mild cognitive impairment), are potential concerns.
dc.language.isoeng
dc.subjectEczacılık
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTemel Eczacılık Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectYaşam Bilimleri
dc.titleTransdermal Scopolamine for the Prevention of Postoperative Nausea and Vomiting: A Systematic Review and Meta-Analysis
dc.typeMakale
dc.relation.journalCLINICAL THERAPEUTICS
dc.contributor.department, ,
dc.identifier.volume32
dc.identifier.issue12
dc.identifier.startpage1987
dc.identifier.endpage2002
dc.contributor.firstauthorID93708


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