dc.contributor.author | Yalin, Serkan Feyyaz | |
dc.contributor.author | Seyahi, Nurhan | |
dc.contributor.author | Durak, Haydar | |
dc.contributor.author | Altiparmak, Mehmet Riza | |
dc.contributor.author | Trabulus, Sinan | |
dc.contributor.author | Oruc, Meric | |
dc.date.accessioned | 2021-03-03T16:56:03Z | |
dc.date.available | 2021-03-03T16:56:03Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Oruc M., Durak H., Yalin S. F. , Seyahi N., Altiparmak M. R. , Trabulus S., "A Rare Presentation of Immunoglobulin A Nephropathy: Acute Kidney Injury", NEPHRON, cilt.137, sa.1, ss.8-14, 2017 | |
dc.identifier.issn | 1660-8151 | |
dc.identifier.other | av_4709def5-26f2-4410-8329-64bd97517ce0 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/51318 | |
dc.identifier.uri | https://doi.org/10.1159/000470852 | |
dc.description.abstract | Background: Acute kidney injury (AKI) is known as an uncommon presentation in immunoglobulin A nephropathy (IgAN). The aim of our study was to analyze the clinical data and biopsy findings in IgAN patients presenting with AKI. Methods: We performed a retrospective analysis of all subjects who had biopsy-proven IgAN and presented with AKI during June 2002 September 2015. The following data were obtained from medical records. Results: A total of 15 patients of 123 patients (12.2%) with primary IgAN admitted with AKI. Patients were generally male (73.3%), with a median age of 38 (interquartile range; IQR, 2,944) years. The serum creatinine at admission was above the normal range (median 2.3 [IQR, 2.14.7] mg/dL]). On histology, cellular/fibrocellular crescents were present in 6 patients. In most cases (53.3%), pathologic abnormalities associated with acute tubular injury/necrosis were defined. Red blood cell casts in tubules were present in 6 cases (40%). In all cases, interstitial mixed inflammatory cell infiltration was observed. In 4 cases, admixed eosinophils were also found. In 3 patients, biopsy specimens showed acute thrombotic microangiopathy lesions (20%). Median follow-up time was 13 (IQR, 346) months. Six patients (40%) progressed to end-stage renal disease ESRD). Among patients diagnosed with primary IgAN and presenting without AKI, only 4 patients progressed to ESRD. The proportion of patients who progressed to ESRD presenting with AKI was significantly higher than the patients presenting without AKI (p = 0.000). Conclusions: In conclusion, AKI complicates IgAN more often. (C) 2017 S. Karger AG, Basel | |
dc.language.iso | eng | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Nefroloji | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | İç Hastalıkları | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | ÜROLOJİ VE NEFROLOJİ | |
dc.title | A Rare Presentation of Immunoglobulin A Nephropathy: Acute Kidney Injury | |
dc.type | Makale | |
dc.relation.journal | NEPHRON | |
dc.contributor.department | İstanbul Üniversitesi , , | |
dc.identifier.volume | 137 | |
dc.identifier.issue | 1 | |
dc.identifier.startpage | 8 | |
dc.identifier.endpage | 14 | |
dc.contributor.firstauthorID | 40489 | |