Discontinuation of RAAS Inhibition in Children with Advanced CKD

Date
2020
Author
van den Belt, Sophie M.
Schaefer, Franz
Querfeld, Uwe
Melk, Anette
de Zeeuw, Dick
Wuehl, Elke
Gellermann, Jutta
ERDOĞAN, HAKAN
Fidan, Kibriya
ÖZÇAKAR, ZEYNEP BİRSİN
Paripovic, Dusan
Shroff, Rukshana
Bacchetta, Justine
DÜZOVA, ALİ
Azukaitis, Karolis
KAPLAN BULUT, İPEK
CANPOLAT, Nur
Niemirska, Anna
KARABAY BAYAZIT, AYSUN
Thurn-Valsassina, Daniela
Gracchi, Valentina
Kirchner, Marietta
Heerspink, Hiddo J. L.
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Abstract
Background and objectives Although renin-angiotensin-aldosterone system inhibition (RAASi) is a cornerstone in the treatment of children with CKD, it is sometimes discontinued when kidney function declines. We studied the reasons of RAASi discontinuation and associations between RAASi discontinuation and important risk markers of CKD progression and on eGFR decline in the Cardiovascular Comorbidity in Children with CKD study.
URI
http://hdl.handle.net/20.500.12627/5065
https://doi.org/10.2215/cjn.09750819
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