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Association between MTHFR C677T polymorphism and folate, vitamin B12, homocysteine, and DNA fragmentation in patients with ovarian cancer

dc.contributor.authorCetin, Ahmet
dc.contributor.authorOzkilic, Anil Cagla
dc.contributor.authorBayoglu, Burcu
dc.contributor.authorCengiz, Mujgan
dc.contributor.authorBalci, Huriye
dc.date.accessioned2021-03-03T16:06:19Z
dc.date.available2021-03-03T16:06:19Z
dc.date.issued2016
dc.identifier.citationOzkilic A. C. , Cetin A., Bayoglu B., Balci H., Cengiz M., "Association between MTHFR C677T polymorphism and folate, vitamin B12, homocysteine, and DNA fragmentation in patients with ovarian cancer", TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.41, sa.6, ss.459-465, 2016
dc.identifier.issn0250-4685
dc.identifier.otherav_4270844a-298d-4852-9047-b9b57d826dda
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/48391
dc.identifier.urihttps://doi.org/10.1515/tjb-2016-0151
dc.description.abstractObjective: Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme that regulates the metabolism of methionine and folate. MTHFR C677T polymorphism was reported to be associated with breast and ovarian cancer. The aim of this study was to evaluate the association between the MTHFR C677T (rs1801133) polymorphism and homocysteine, vitamin B-12, and folate levels, and DNA fragmentation in patients with ovarian cancer and healthy controls.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectSitogenetik
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.titleAssociation between MTHFR C677T polymorphism and folate, vitamin B12, homocysteine, and DNA fragmentation in patients with ovarian cancer
dc.typeMakale
dc.relation.journalTURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
dc.contributor.departmentIstanbul Haseki Training & Research Hospital , ,
dc.identifier.volume41
dc.identifier.issue6
dc.identifier.startpage459
dc.identifier.endpage465
dc.contributor.firstauthorID237400


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