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Predictors of treatment requirement in HBeAg-negative chronic hepatitis B patients with persistently normal alanine aminotransferase and high serum HBV DNA levels

dc.contributor.authorPinarbasi, Binnur
dc.contributor.authorBadur, Selim
dc.contributor.authorKaymakoglu, Sabahattin
dc.contributor.authorDemir, Kadir
dc.contributor.authorBesisik, Fatih
dc.contributor.authorGulluoglu, Mine
dc.contributor.authorSumnu, Abdullah
dc.contributor.authorAkyuz, Filiz
dc.contributor.authorBaran, Bulent
dc.contributor.authorGokturk, Suut
dc.contributor.authorKaraca, Cetin
dc.contributor.authorOrmeci, Asli
dc.contributor.authorAydın, Yücel
dc.contributor.authorSoyer, Ozlem Mutluay
dc.contributor.authorOnel, Derya
dc.date.accessioned2021-03-03T15:58:21Z
dc.date.available2021-03-03T15:58:21Z
dc.identifier.citationOrmeci A., Aydın Y., Sumnu A., Baran B., Soyer O. M. , Pinarbasi B., Gokturk S., Gulluoglu M., Onel D., Badur S., et al., "Predictors of treatment requirement in HBeAg-negative chronic hepatitis B patients with persistently normal alanine aminotransferase and high serum HBV DNA levels", International Journal of Infectious Diseases, cilt.52, ss.68-73, 2016
dc.identifier.issn1201-9712
dc.identifier.otherav_41be6047-1b95-4f0f-bd64-82cdea869ecd
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/47929
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84993978170&origin=inward
dc.identifier.urihttps://doi.org/10.1016/j.ijid.2016.09.007
dc.description.abstractObjectives: Serum alanine aminotransferase (ALT) is a controversial marker for disease monitoring in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) patients. The aim of this study was to determine the fibrosis stage and histological activity index (HAI) in HBeAg-negative CHB patients with persistently normal ALT (PNALT) and high serum HBV DNA (>= 2000 IU/ml) and to investigate clinical risk factors for the requirement of treatment through the examination of liver biopsy specimens.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectİmmünoloji
dc.subjectBULAŞICI HASTALIKLAR
dc.subjectYaşam Bilimleri
dc.titlePredictors of treatment requirement in HBeAg-negative chronic hepatitis B patients with persistently normal alanine aminotransferase and high serum HBV DNA levels
dc.typeMakale
dc.relation.journalInternational Journal of Infectious Diseases
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume52
dc.identifier.startpage68
dc.identifier.endpage73
dc.contributor.firstauthorID236482


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