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Polymorphisms of the DNA Repair Genes XPD and XRCC1 and the Risk of Age-Related Macular Degeneration

dc.contributor.authorSeven, Mehmet
dc.contributor.authorGuven, Gulgun S.
dc.contributor.authorGuven, Mehmet
dc.contributor.authorGorgun, Ebru
dc.contributor.authorÜNAL, MUSTAFA
dc.contributor.authorYenerel, Melda
dc.contributor.authorTatlipinar, Sinan
dc.contributor.authorYuksel, Adnan
dc.contributor.authorBatar, Bahadir
dc.date.accessioned2021-03-03T15:39:13Z
dc.date.available2021-03-03T15:39:13Z
dc.date.issued2010
dc.identifier.citationGorgun E., Guven M., ÜNAL M., Batar B., Guven G. S. , Yenerel M., Tatlipinar S., Seven M., Yuksel A., "Polymorphisms of the DNA Repair Genes XPD and XRCC1 and the Risk of Age-Related Macular Degeneration", INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, cilt.51, sa.9, ss.4732-4737, 2010
dc.identifier.issn0146-0404
dc.identifier.othervv_1032021
dc.identifier.otherav_4011b74c-aa0a-4c22-bf15-07ffdd081b7f
dc.identifier.urihttp://hdl.handle.net/20.500.12627/46838
dc.identifier.urihttps://doi.org/10.1167/iovs.09-4842
dc.description.abstractPURPOSE. Oxidative stress seems to be an important factor in the development of age-related macular degeneration (AMD). The role of DNA repair mechanisms has also received attention recently in AMD pathogenesis. This case-control study was conducted to determine the frequency of polymorphisms in two DNA repair enzyme genes, xeroderma pigmentosum complementation group D (XPD), codons 312 and 751, and x-ray cross-complementing group 1 (XRCC1), codons 194 and 399, in patients with AMD and in disease-free control subjects.
dc.language.isoeng
dc.subjectGöz Hastalıkları ve Cerrahisi
dc.subjectOFTALMOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectCerrahi Tıp Bilimleri
dc.titlePolymorphisms of the DNA Repair Genes XPD and XRCC1 and the Risk of Age-Related Macular Degeneration
dc.typeMakale
dc.relation.journalINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
dc.contributor.departmentYeditepe Üniversitesi , ,
dc.identifier.volume51
dc.identifier.issue9
dc.identifier.startpage4732
dc.identifier.endpage4737
dc.contributor.firstauthorID14803


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