dc.contributor.author | AYKAC-TOKER, G | |
dc.contributor.author | Dogru-Abbasoglu, Semra | |
dc.contributor.author | Erbil, Yeşim | |
dc.contributor.author | TURKOGLU, S | |
dc.contributor.author | BARBAROS, U | |
dc.contributor.author | Uysal, Mehmet Müjdat | |
dc.contributor.author | Mutlu-Turkoglu, U | |
dc.date.accessioned | 2021-03-03T13:49:00Z | |
dc.date.available | 2021-03-03T13:49:00Z | |
dc.date.issued | 2002 | |
dc.identifier.citation | Dogru-Abbasoglu S., Mutlu-Turkoglu U., TURKOGLU S., Erbil Y., BARBAROS U., Uysal M. M. , AYKAC-TOKER G., "Glutathione S-transferase-pi in malignant tissues and plasma of human colorectal and gastric cancers", JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, cilt.128, sa.2, ss.91-95, 2002 | |
dc.identifier.issn | 0171-5216 | |
dc.identifier.other | av_362e073e-58eb-4d57-80bb-e5de1af59e15 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/40592 | |
dc.identifier.uri | https://doi.org/10.1007/s00432-001-0300-7 | |
dc.description.abstract | Purpose: In this study, 16 paired samples of colorectal and gastric cancers and adjacent non-neoplastic tissues were analysed for the determination of glutathione S-transferase (GST) activities and the expression of GST-pi. Methods: Western blotting procedure as well as plasma GST-pi levels were used. Results: GST activities were found to be increased in malignant tissues of patient compared with adjacent normal tissues. A significant correlation was detected between GST activity and GST-pi expression in malignant tissues of patients. Plasma GST-pi levels increased in patients compared to aged-matched control subjects. When the patients were grouped according to TNM stage, GST-pi expression in malignant tissues as well as plasma GST-pi levels were higher in patients with more advanced tumor stages. Conclusions: Our results indicate that GST-pi expression in malignant tissues and plasma GST-pi levels in human colorectal and gastric cancers increased depending on the stages of tumor. | |
dc.language.iso | eng | |
dc.subject | Onkoloji | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | İç Hastalıkları | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | ONKOLOJİ | |
dc.title | Glutathione S-transferase-pi in malignant tissues and plasma of human colorectal and gastric cancers | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY | |
dc.contributor.department | , , | |
dc.identifier.volume | 128 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 91 | |
dc.identifier.endpage | 95 | |
dc.contributor.firstauthorID | 44855 | |