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dc.contributor.authorAttar, Ruekset
dc.contributor.authorIyibozkurt, Ahmet Cem
dc.contributor.authorBulgurcuoglu, Sibel
dc.contributor.authorArslan, Burcu Kardas
dc.contributor.authorAttar, Erkut
dc.contributor.authorBalcik, Pelin
dc.date.accessioned2021-03-03T12:32:13Z
dc.date.available2021-03-03T12:32:13Z
dc.date.issued2009
dc.identifier.citationIyibozkurt A. C. , Balcik P., Bulgurcuoglu S., Arslan B. K. , Attar R., Attar E., "Effect of vascular endothelial growth factor on sperm motility and survival", REPRODUCTIVE BIOMEDICINE ONLINE, cilt.19, sa.6, ss.784-788, 2009
dc.identifier.issn1472-6483
dc.identifier.otherav_2ead3425-f18f-4088-ba52-1cdc1ffec637
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/35911
dc.identifier.urihttps://doi.org/10.1016/j.rbmo.2009.09.019
dc.description.abstractVascular endothelial growth factor (VEGF) and its receptors are present in both male and female reproductive Systems. In this experimental study.. the effect of different concentrations of VEGF on sperm motility and survival in vitro was investigated. Human spermatozoa, collected from voluntary, proven fertile donors, were incubated in sperm washing medium containing different concentrations of VEGF (5, 10, 15, 20 ng/ml) for 24 h in a university reproductive endocrinology laboratory setting. Assessment of VEGF action on sperm motion characteristics was evaluated using a computer-assisted semen analyser. Sperm survival was determined by hypo-osmotic swelling and eosin-Y dye tests. VEGF had a positive effect on some parameters of sperm motility in a concentration-dependent manner. Maximal effect was observed at a concentration of 15 ng/ml; motility, progression, straight-line velocity and curvilinear velocity of VEGF-exposed spermatozoa were significantly increased (P < 0.05) at this concentration. However, sperm viability was not prolonged at any concentration of VEGF as shown by hypo-osmotic swelling and eosin-Y dye tests. VEGF may increase some sperm motility parameters, but not survival, in a concentration-dependent manner in vitro.
dc.language.isoeng
dc.subjectTemel Tıp Bilimleri
dc.subjectBiyokimya
dc.subjectCerrahi Tıp Bilimleri
dc.subjectKadın Hastalıkları ve Doğum
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectKlinik Tıp
dc.subjectBiyoloji ve Biyokimya
dc.subjectKADIN HASTALIKLARI & DOĞUM
dc.subjectÜREME BİYOLOJİSİ
dc.subjectKlinik Tıp (MED)
dc.titleEffect of vascular endothelial growth factor on sperm motility and survival
dc.typeMakale
dc.relation.journalREPRODUCTIVE BIOMEDICINE ONLINE
dc.contributor.departmentYeditepe Üniversitesi , ,
dc.identifier.volume19
dc.identifier.issue6
dc.identifier.startpage784
dc.identifier.endpage788
dc.contributor.firstauthorID25379


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