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dc.contributor.authorSener, Leyla
dc.contributor.authorAlbeniz, Isil
dc.contributor.authorDinc, Bircan
dc.contributor.authorAlbeniz, Gurcan
dc.date.accessioned2021-03-03T12:06:28Z
dc.date.available2021-03-03T12:06:28Z
dc.date.issued2017
dc.identifier.citationSener L., Albeniz G., Dinc B., Albeniz I., "iCELLigence real-time cell analysis system for examining the cytotoxicity of drugs to cancer cell lines.", Experimental and therapeutic medicine, cilt.14, sa.3, ss.1866-1870, 2017
dc.identifier.issn1792-0981
dc.identifier.othervv_1032021
dc.identifier.otherav_2be35ca0-fe85-46ba-b5d2-cf352e5b38d1
dc.identifier.urihttp://hdl.handle.net/20.500.12627/34248
dc.identifier.urihttps://doi.org/10.3892/etm.2017.4781
dc.description.abstractThe recently developed iCELLigence (TM) real-time cell analyzer (RTCA) can be used for the label-free real-time monitoring of cancer cell proliferation, viability, invasion and cytotoxicity. The RTCA system uses 16-well microtiter plates with a gold microelectrode biosensor array that measures impedance when cells adhere to the microelectrodes causing an alternating current. By measuring the electric field generated in this process, the RTCA system can be used for the analysis of cell proliferation, viability, morphology and migration. The present review aimed to summarize the working method of the RTCA system, in addition to discussing the research performed using the system for various applications, including cancer drug discovery via measuring cytotoxicity.
dc.language.isoeng
dc.subjectTIP, ARAŞTIRMA VE DENEYSEL
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectDahili Tıp Bilimleri
dc.subjectTıbbi Ekoloji ve Hidroklimatoloji
dc.subjectSağlık Bilimleri
dc.titleiCELLigence real-time cell analysis system for examining the cytotoxicity of drugs to cancer cell lines.
dc.typeMakale
dc.relation.journalExperimental and therapeutic medicine
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume14
dc.identifier.issue3
dc.identifier.startpage1866
dc.identifier.endpage1870
dc.contributor.firstauthorID245474


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