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Immunomagnetic separation of B type acute lymphoblastic leukemia cells from bone marrow with flow cytometry validation and microfluidic chip measurements

dc.contributor.authorDeniz, Günnur
dc.contributor.authorEken, Ahmet
dc.contributor.authorÇınar, Suzan
dc.contributor.authorMurat, Ayşegül
dc.contributor.authorÖzcan, Servet
dc.contributor.authorÜnal, Ekrem
dc.contributor.authorİçöz, Kutay
dc.date.accessioned2021-03-02T16:31:27Z
dc.date.available2021-03-02T16:31:27Z
dc.identifier.citationİçöz K., Eken A., Çınar S., Murat A., Özcan S., Ünal E., Deniz G., "Immunomagnetic separation of B type acute lymphoblastic leukemia cells from bone marrow with flow cytometry validation and microfluidic chip measurements", Separation Science And Technology, cilt.55, ss.1-8, 2020
dc.identifier.issn0149-6395
dc.identifier.othervv_1032021
dc.identifier.otherav_e80e7508-0f3c-4930-b8c4-6c9e79aae1b9
dc.identifier.urihttp://hdl.handle.net/20.500.12627/3079
dc.identifier.urihttps://doi.org/10.1080/01496395.2020.1835983
dc.identifier.urihttps://doi.org/10.1080/01496395.2020.1835983
dc.description.abstractIn order to detect the blast cells from bone marrow of patients, one strategy is to first isolate the cells using immunomagnetic beads. The aim of this study was to report the experimental results of the immunomagnetic separation efficiency of the blast cells from bone marrow of pediatric leukemia patients. To test the efficiency of immunomagnetic separation, flow cytometry measurements at critical steps were performed. We here reported 94.5% capture efficiency for CD10 nano beads. Patients samples were also analyzed with a microfluidic chip to test the feasibility for further developments.
dc.language.isoeng
dc.subjectÇocuk Sağlığı ve Hastalıkları
dc.subjectPediatrik Hematoloji
dc.subjectBiyoteknoloji
dc.subjectBiyomedikal Mühendislik
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectKimya Mühendisliği ve Teknolojisi
dc.subjectKlinik Tıp (MED)
dc.subjectMühendislik, Bilişim ve Teknoloji (ENG)
dc.subjectTemel Bilimler (SCI)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectKlinik Tıp
dc.subjectMühendislik
dc.subjectDoğa Bilimleri Genel
dc.subjectİmmünoloji
dc.subjectMikrobiyoloji
dc.subjectTIP, GENEL & İÇECEK
dc.subjectPEDİATRİ
dc.subjectMÜHENDİSLİK, KİMYASAL
dc.subjectÇOK DİSİPLİNLİ BİLİMLER
dc.subjectİMMÜNOLOJİ
dc.subjectMİKROBİYOLOJİ
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.titleImmunomagnetic separation of B type acute lymphoblastic leukemia cells from bone marrow with flow cytometry validation and microfluidic chip measurements
dc.typeMakale
dc.relation.journalSeparation Science And Technology
dc.contributor.departmentAbdullah Gül Üniversitesi , Mühendislik Fakültesi , Elektrik-Elektronik Mühendisliği
dc.identifier.volume55
dc.identifier.startpage1
dc.identifier.endpage8
dc.contributor.firstauthorID2273815


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