Show simple item record

dc.contributor.authorBayırlı, Gündüz
dc.contributor.authorErsev, Handan
dc.contributor.authorSchweikl, Helmut
dc.contributor.authorSchmalz, Gottfried
dc.date.accessioned2021-03-03T10:27:57Z
dc.date.available2021-03-03T10:27:57Z
dc.date.issued1999
dc.identifier.citationErsev H., Schmalz G., Bayırlı G., Schweikl H., "Cytotoxic and mutagenic potencies of various root canal filling materials in eukaryotic and prokaryotic cells in vitro", JOURNAL OF ENDODONTICS, cilt.25, sa.5, ss.359-363, 1999
dc.identifier.issn0099-2399
dc.identifier.otherav_22bbe81c-81d1-4d80-8755-7da88bf66f24
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/28355
dc.identifier.urihttps://doi.org/10.1016/s0099-2399(06)81172-6
dc.description.abstractCytotoxic and mutagenic effects of root canal filling cements of various chemical composition were determined in vitro. Materials set for 24 h and 1 wk were eluted for 24 h in cell culture medium (cytotoxicity testing) and dimethyl sulfoxide or physiological saline (mutagenicity testing). The differences between cytotoxic potencies of eluates of the endodontic materials on L-929 cells were quantified colorimetrically (MTT test). Eluates of Traitment SPAD were about 5- to 30-fold more toxic than silver-free AH26, TubliSeal, CRCS, and Endomethsone N. The rank order of the toxic effects depended on the setting time of mixed materials. Dimethyl sulfoxide and saline eluates of Traitment SPAD, Tubli-Seal, Endomethasone N, CRCS, and Ketac-Endo were not mutagenic in the Ames test. Both eluates of silver-free AH26 set for 24 h were weakly mutagenic in Salmonella typhimurium TA100. Weak mutagenicity of saline eluates of the material was also observed in TA97a and TA102. These results point to the possibility that mixed silver-free AH26 might contain small amounts of two mutagenic substances: bisphenol A diglycidyl ether and formaldehyde.
dc.language.isoeng
dc.subjectKlinik Tıp (MED)
dc.subjectSağlık Bilimleri
dc.subjectDİŞ HEKİMLİĞİ, ORAL CERRAHİ VE TIP
dc.subjectKlinik Tıp
dc.subjectTıp
dc.subjectDiş Hekimliği
dc.titleCytotoxic and mutagenic potencies of various root canal filling materials in eukaryotic and prokaryotic cells in vitro
dc.typeMakale
dc.relation.journalJOURNAL OF ENDODONTICS
dc.contributor.department, ,
dc.identifier.volume25
dc.identifier.issue5
dc.identifier.startpage359
dc.identifier.endpage363
dc.contributor.firstauthorID54315


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record