Basit öğe kaydını göster

dc.contributor.authorErcan, M
dc.contributor.authorOnen, S
dc.contributor.authorAyaz, M
dc.contributor.authorKonukoglu, D
dc.date.accessioned2021-03-03T09:49:43Z
dc.date.available2021-03-03T09:49:43Z
dc.identifier.citationKonukoglu D., Ercan M., Ayaz M., Onen S., "Plasma and erythrocytes antioxidant status and trace element levels in proteinuric patients with moderate glomerular function", JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, cilt.15, ss.119-122, 2001
dc.identifier.issn0946-672X
dc.identifier.othervv_1032021
dc.identifier.otherav_1f1952d5-41b7-4de8-a0fa-b0faaa91d5b2
dc.identifier.urihttp://hdl.handle.net/20.500.12627/26041
dc.identifier.urihttps://doi.org/10.1016/s0946-672x(01)80054-7
dc.description.abstractThe objective of the study was to investigate the effect of moderate glomerular dysfunction on oxidative stress. We determined the plasma and erythrocyte malondialdehyde (MDA) Levels, as a marker of lipid peroxidation, erythrocyte glutathione (GSH) levels and activities of GSH-Px, GSH Red and SOD as an antioxidant enzymes, and plasma trace element levels containing Fe, Cu and Zn in twenty proteinuric patients (6.8 +/- 5.1 g/day) with moderate glomerular function and in 20 anemic control subjects. We found that the erythrocyte and plasma MDA levels and erythrocyte GSH-Px activities were significantly higher (p < 0.001, p < 0.001, p < 0.001, respectively) and the erythrocyte GSH levels and activities of GSH-Red and SOD activities were significantly lower (p < 0.001, p < 0.001, p < 0.001, respectively) in the patients than in the anemic subjects. Plasma Fe and Zn Levels were not to be found significantly different in the patients compared to the anemic subjects. But plasma Cu levels were significantly higher in the patients (p < 0.05) when compared with the levels of anemic subjects. This study was concluded that cellular antioxidant activity decreases in proteinuric patients with moderate glomerular function. This may increase lipid peroxidation reactions by causing oxidative stress in erythrocyte membranes.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectEndokrinoloji ve Metabolizma Hastalıkları
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectKlinik Tıp
dc.subjectENDOKRİNOLOJİ VE METABOLİZMA
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.titlePlasma and erythrocytes antioxidant status and trace element levels in proteinuric patients with moderate glomerular function
dc.typeMakale
dc.relation.journalJOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
dc.contributor.department, ,
dc.identifier.volume15
dc.identifier.startpage119
dc.identifier.endpage122
dc.contributor.firstauthorID127308


Bu öğenin dosyaları:

DosyalarBoyutBiçimGöster

Bu öğe ile ilişkili dosya yok.

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster