dc.contributor.author | Alikasifoglu, M. | |
dc.contributor.author | Ercan, O. | |
dc.contributor.author | Erginoz, E. | |
dc.contributor.author | Güneş, Ece Olcay | |
dc.date.accessioned | 2023-02-21T10:35:05Z | |
dc.date.available | 2023-02-21T10:35:05Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Güneş E. O., Alikasifoglu M., Erginoz E., Ercan O., "Relationship Between TSH Level and Cardiometabolic Risk Factors in Overweight and Obese Adolescents", HONG KONG JOURNAL OF PAEDIATRICS, cilt.27, sa.4, ss.226-232, 2022 | |
dc.identifier.issn | 1013-9923 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_472da82d-ba04-477f-b038-0b5bb15a34e1 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/188529 | |
dc.description.abstract | Purpose: To investigate the relationship between TSH levels and cardiometabolic risk factors in overweight/obese adolescents by gender. Methods: We performed a retrospective cross-sectional analysis of the data from 343 overweight/obese adolescents aged between 11 and 18 years. The degree of obesity was calculated as the body mass index standard deviation score (BMI-SDS). Hypertension, dyslipidaemia, hyperinsulinaemia, hyperglycaemia and insulin resistance were defined as cardiometabolic risk factors. The patients' TSH and free T4 levels were recorded, and the subjects with normal free T4 levels were included. Findings: A positive correlation was found between TSH level and homeostatic model assessment of insulin resistance (HOMA-IR), insulin and triglyceride levels (p=0.001, 0.001, 0.006, respectively). In the linear regression analysis, in which age, gender and BMI-SDS values were taken as covariates, a 10% increase in the geometric mean of TSH was associated with a 0.13 fold increase in HOMA-IR, and a 10% increase in TSH level was associated with a onefold increase in geometric mean of insulin level (p=0.003, 0.002, respectively), but the relationship between TSH and triglyceride levels disappeared. Conclusions: TSH levels were found to be related to the glucose metabolism. Further prospective studies are needed to clarify the mechanism of this relationship. | |
dc.language.iso | eng | |
dc.subject | Pediatri | |
dc.subject | Pediatri, Perinatoloji ve Çocuk Sağlığı | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Çocuk Sağlığı ve Hastalıkları | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | PEDİATRİ | |
dc.title | Relationship Between TSH Level and Cardiometabolic Risk Factors in Overweight and Obese Adolescents | |
dc.type | Makale | |
dc.relation.journal | HONG KONG JOURNAL OF PAEDIATRICS | |
dc.contributor.department | İstanbul Teknik Üniversitesi , Elektrik-Elektronik , Elektronik Ve Haberleşme Mühendisliği | |
dc.identifier.volume | 27 | |
dc.identifier.issue | 4 | |
dc.identifier.startpage | 226 | |
dc.identifier.endpage | 232 | |
dc.contributor.firstauthorID | 4078944 | |