dc.contributor.author | Onal, Pinar | |
dc.contributor.author | Cicek, Alper | |
dc.contributor.author | ŞAHİN, SABİHA | |
dc.contributor.author | KIZIL, MAHMUT CAN | |
dc.contributor.author | KARA, YALÇIN | |
dc.contributor.author | Apa, Hursit | |
dc.contributor.author | Ulusoy, Emel | |
dc.contributor.author | Kara, Aybuke Akaslan | |
dc.contributor.author | Yesil, Edanur | |
dc.contributor.author | Erdem, Meltem | |
dc.contributor.author | Turan, Caner | |
dc.contributor.author | ARSLANOĞLU, Sertaç | |
dc.contributor.author | Duyu, Muhterem | |
dc.contributor.author | BESLİ, GÜLSER ESEN | |
dc.contributor.author | Arslan, Gazi | |
dc.contributor.author | Oflu, Ayse Tolunay | |
dc.contributor.author | Celegen, Mehmet | |
dc.contributor.author | Buldu, Ebru | |
dc.contributor.author | PİŞKİN, İBRAHİM ETEM | |
dc.contributor.author | Kardes, Hakan | |
dc.contributor.author | YILMAZ, HAYRİ LEVENT | |
dc.contributor.author | Yildizdas, Dincer | |
dc.contributor.author | Gokulu, Gamze | |
dc.contributor.author | Cay, Pinar | |
dc.contributor.author | Ozer, Utku | |
dc.contributor.author | DERİNÖZ GÜLERYÜZ, OKŞAN | |
dc.contributor.author | ÇOLAK, ÖZLEM | |
dc.contributor.author | TOMAR GÜNEYSU, SONGÜL | |
dc.contributor.author | Yildiz, Raif | |
dc.contributor.author | DUMAN, MURAT | |
dc.contributor.author | ŞIK, NİHAN | |
dc.contributor.author | TEKŞAM, ÖZLEM | |
dc.contributor.author | Akca, Halise | |
dc.contributor.author | Kurt, Funda | |
dc.contributor.author | Caglar, Ayla Akca | |
dc.contributor.author | Yildiz, Leman Akcan | |
dc.contributor.author | Tasar, Medine Aysin | |
dc.contributor.author | Fidanci, Ilknur | |
dc.contributor.author | Yayla, Burcu Ceylan Cura | |
dc.contributor.author | YILMAZ, DURGÜL | |
dc.contributor.author | GÜNGÖR, EMRE | |
dc.contributor.author | Demir, Sule | |
dc.contributor.author | ÇOKUĞRAŞ, HALUK CEZMİ | |
dc.contributor.author | ORAL CEBECİ, SİNEM | |
dc.contributor.author | SAZ, EYLEM ULAŞ | |
dc.contributor.author | YURTSEVEN, ALİ | |
dc.contributor.author | Uysalol, Metin | |
dc.contributor.author | Gumus, Suheyla | |
dc.contributor.author | BAL, ALKAN | |
dc.contributor.author | Sen Bayturan, Semra | |
dc.contributor.author | Zengin, Neslihan | |
dc.contributor.author | Atik, Sinem | |
dc.contributor.author | Ciftdogan, Dilek Yilmaz | |
dc.contributor.author | Berksoy, Emel | |
dc.date.accessioned | 2023-02-21T07:37:59Z | |
dc.date.available | 2023-02-21T07:37:59Z | |
dc.identifier.citation | DUMAN M., ŞIK N., TEKŞAM Ö., Akca H., Kurt F., Caglar A. A., Yildiz L. A., Tasar M. A., Fidanci I., Yayla B. C. C., et al., "COVID-19 disease in children presenting to the pediatric emergency department: A multicenter study with 8886 cases from Turkey", AMERICAN JOURNAL OF EMERGENCY MEDICINE, cilt.59, ss.133-140, 2022 | |
dc.identifier.issn | 0735-6757 | |
dc.identifier.other | av_0a0b7e0f-983b-47b1-bd2f-1ad928269917 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/185965 | |
dc.identifier.uri | https://doi.org/10.1016/j.ajem.2022.06.015 | |
dc.description.abstract | Background: The aim was to evaluate the epidemiological, clinical, laboratory, and radiologic data of children with SARS-CoV-2 positivity by polymerase chain reaction (PCR) together with treatment strategies and clinical out-comes and to evaluate cases of multisystem inflammatory syndrome in children (MIS-C) in this population.Methods: This was a multicenter retrospective observational cohort study performed in the pediatric emergency departments of 19 tertiary hospitals. From March 11, 2020, to May 31, 2021, children who were diagnosed with confirmed nasopharyngeal/tracheal specimen SARS-CoV-2 PCR positivity or positivity for serum-specific anti-bodies against SARS-CoV-2 were included. Demographics, presence of chronic illness, symptoms, history of con-tact with SARS-CoV-2 PCR-positive individuals, laboratory and radiologic investigations, clinical severity, hospital admissions, and prognosis were recorded.Results: A total of 8886 cases were included. While 8799 (99.0%) cases resulted in a diagnosis of SARS-CoV-2 with PCR positivity, 87 (1.0%) patients were diagnosed with MIS-C. Among SARS-CoV-2 PCR-positive patients, 51.0% were male and 8.5% had chronic illnesses. The median age was 11.6 years (IQR: 5.0-15.4) and 737 (8.4%) patients were aged <1 year. Of the patients, 15.5% were asymptomatic. The most common symptoms were fever (48.5%) and cough (30.7%) for all age groups. There was a decrease in the rate of fever as age increased (p < 0.001); the most common age group for this symptom was <1 year with the rate of 69.6%. There was known contact with a SARS-CoV-2 PCR-positive individual in 67.3% of the cases, with household contacts in 71.3% of those cases. In terms of clinical severity, 83 (0.9%) patients were in the severe-critical group. There was hospital admission in 1269 (14.4%) cases, with 106 (1.2%) of those patients being admitted to the pediatric intensive care unit (PICU). Among patients with MIS-C, 60.9% were male and the median age was 6.4 years (IQR: 3.9-10.4). Twelve (13.7%) patients presented with shock. There was hospital admission in 89.7% of these cases, with 29.9% of the patients with MIS-C being admitted to the PICU.Conclusion: Most SARS-CoV-2 PCR-positive patients presented with a mild clinical course. Although rare, MIS-C emerges as a serious consequence with frequent PICU admission. Further understanding of the characteristics of COVID-19 disease could provide insights and guide the development of therapeutic strategies for target groups.(c) 2022 Elsevier Inc. All rights reserved. | |
dc.language.iso | eng | |
dc.subject | Tıp | |
dc.subject | ACİL TIP | |
dc.subject | Klinik Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Cerrahi Tıp Bilimleri | |
dc.subject | Acil Tıp | |
dc.subject | Acil Tıp Hizmetleri | |
dc.title | COVID-19 disease in children presenting to the pediatric emergency department: A multicenter study with 8886 cases from Turkey | |
dc.type | Makale | |
dc.relation.journal | AMERICAN JOURNAL OF EMERGENCY MEDICINE | |
dc.contributor.department | Dokuz Eylül Üniversitesi , Tıp Fakültesi , Dahili Tıp Bilimleri Bölümü | |
dc.identifier.volume | 59 | |
dc.identifier.startpage | 133 | |
dc.identifier.endpage | 140 | |
dc.contributor.firstauthorID | 3450495 | |